Santai SepaBean Automated Flash Instrument
The SepaBean machine is an innovative flash chromatography instrument designed specifically with the chemist in mind. Its unique user-friendly software interface allows seamless data collection and sharing as well as remote access.
- Wireless Operation Through Mobile Devices
The flexible wireless control method is especially suitable for separation experiments that need to be protected from light or placed in an isolator. - Power Failure Recovery
The built-in power-off recovery function in the software minimises the loss caused by accidental power failure. - Smart Column Holder
Column holder with touchpad could achieve automatic fixing of the flash column.* - Fraction Collector
Tube racks with LCD enable users to track the tubes containing collected fractions quickly. - Separation Method Recommendation
The software has a built-in separation method database that automatically recommends the most appropriate separation method based on the user’s information, thereby improving work efficiency. - Local Network Data Sharing
Multiple instruments could form a local area network to facilitate internal data sharing and resource optimisation in the laboratory. - 21-CFR Part 11 Compliance
The control software complies with FDA requirements for system safety (21-CFR Part 11), making the instrument more suitable for pharmaceutical R&D companies and laboratories.
Notes:
*Smart column holder is not applicable for SepaBeanTM machine U.
TLC-to-Gradient
With the new TLC-to-Gradient feature built into the control software of the SepaBean machine, the whole sample preparation process can be accelerated. Once you have entered the TLC information and sample load, the software will automatically recommend the best flash column for the separation, and the optimised elution gradient will be generated.
HPLC-to-Gradient
For reversed-phase separation, the control software can also assist the user with smart recommendations. Input the analytical HPLC information, including the retention time of the sample, the percentage of Solvent B when the specific component is eluted out, the peak area of the target product and the primary impurities, the elution gradient will be automatically generated.
Safe Reliable Data Recording & Sharing
All data generated by the SepaBean machine is stored and transmitted by 128/256 bit AES encryption technology and fully controlled by the owner of the machine.
Network ready, multiple instruments within an organisation can form a private channel. Users can share Separation methods across the entire organisation; authorised researchers can access and run these methods directly without re-developing the methods.
Discover and connect to peer instrument automatically. Once multiple instruments are connected, data is automatically synchronised, researchers can access their methods on any connected instrument from any location.
- Models
- Eco-friendly Column Management
- Simple Mobile Interface
- Internal Method Database
- Global Chemistry Database
- Technical Data
- Quote
Models
SepaBean® machine U
Entry-level model with all the features of SepaBean control software. Meet the demands of daily separation and purification, including normal phase and reversed-phase separation.
SepaBean® machine T
Cost-effective model with all features of SepaBean control software. Binary gradient with any combinations of two solvents. Optional ELSD to cover more types of samples.
SepaBean® machine
Standard version. Binary gradient with four solvent lines, high-pressure mixing.Optional ELSD to cover more types of samples.
SepaBean® machine 2
Medium pressure model which could perfectly match with SepaFlash spin-welded columns for higher separation efficiency. Binary gradient with any combinations of two solvents, 3rd solvent as a modifier, able to run complex separation conditions. Optional ELSD to cover more types of samples.
NEW SepaBean® machine 2S
Improved medium pressure model with a higher flow rate, up to 300 mL/min.
Binary gradient with any combinations of two solvents, 3rd solvent as a modifier, able to run complex separation conditions. Optional ELSD to cover more types of samples.
High flow rate model for a large amount of sample purification (1000 ml/min & 150psi), up to 300 grams in a single run. Binary gradient with any combination of two solvents.
Eco-friendly Column Management
Simple Mobile Interface
Internal Method Database
With the built-in relational database to store separation methods, researchers can query existing or update new separation methods using the compound name, structure or project code.
Global Chemistry Database
Technical Data

Sample Weight | mg up to 150g |
Supported Column Size | 4g - 1600g |
Pump | Binary maintenance-free Pumps |
Flow Rate | 1 - 200 mL/min |
Flow Accuracy | +/- 11% |
Max Pressure | 200 psi |
Detector | Dual-wavelength UV/VIS |
Pump Gradient | Linear, Step, Gradient |
Software | Lifetime software update via the App Store |
Dimensions (H x W x D) | 62cm X 40cm X 40cm |
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