Used Waters nanoACQUITY UPLC

Available from KRSS a used fully refurbished and service Waters nanoACQUITY UPLC including optional Auxiliary Solvent Manager and FlexCart.

The Waters nanoACQUITY UPLC System supplies direct (non-split) capillary and nanoflow rates for high-resolution chromatographic separations optimized for columns ranging from 1 mm to 75 μm internal diameter. Core components of the nanoACQUITY UPLC Base System include: nanoACQUITY UPLC Binary Solvent Manager, nanoACQUITY UPLC Sample Manager with integrated heating and trapping module and optional Auxiliary Solvent Manager and FlexCart.

  • Overview
  • System Features
  • Why purchase used refurbished
    mass specs from KRSS
  • Quote


Scientists working in proteomics and biomarker discovery must obtain the most information from very small amounts of highly complex, often irreplaceable samples.

For these analyses, fragmented LC and MS solutions are often the norm, creating a steep learning curve for analysts and less t han ideal results.

With Waters nanoACQUITY UPLC system, you will experience increased reliability and ease-of-use through holistic design, intuitive diagnostics, and customized nano-scale fittings and columns. Experience reproducible, high peak capacity separations that provide better data quality and more confident results. Maximize your laboratory resources with a flexible system designed to work with any mass spectrometer. Break through the limitations of your current nano-scale HPLC system and step into a world of information-rich analyses your laboratory can count on.

A System Built Without Compromise

Built on the groundbreaking technology of Waters ACQUITY UPLC system, nanoACQUITY UPLC is a platform specifically designed for applications that depend on nano-scale separations such as biomolecule identification, post-translational modifications, and biomarker discovery.

System Features

Maximum resolution - Optimized system to drive 1.7 μm BEH particle technology to yield maximum peak capacity for complex mixtures.

Maximum reproducibility - Direct nanoflow control and a novel, moveable heating and trapping module for < 0.25-minute standard deviation run-to-run reproducibility, even over long gradients.

Maximum throughput - BEH Technology columns enable faster
gradient separations for simple mixtures, or when preforming targeted analyses without compromising resolution.

Robustness - Nano-scale columns and fittings (PEEK, 1/32 stainless steel and gold coating) provide reliable operation for up to 10,000 psi, with novel high pressure trapping.

Ease-of-use - Direct gradient control enables minimized tubing assemblies and simplified loading and trapping schemes.

Enhanced on-board diagnostics - Efficiently monitor system performance.

Combine with any MS - Control the nanoACQUITY UPLC system from your Waters, Thermo Fisher Scientific, or ABI/MDS SCIEX mass spectrometer software platforms.

UPLC and HPLC - Compatible with a wide range of conventional nano-scale columns with a flow rate range from 200 nL/min to 100 μL/min

Flexibility to suit your separation needs

The direct nano-flow design of the nanoACQUITY UPLC system run without a flow-splitter, removing the need to adjust fittings and perform flow calibrations just to change the flow rate. With this easy-to-use system, you’ll see better robustness and chromatographic reproducibility.

Reproducibility never seen before at nano-scale

Improve accuracy in qualitative and quantitative applications - the unparalleled run-to-run reproducibility (even over long gradients) of the nanoACQUIT Y UPLC system’s direct nano-flow functionality is essential for components to be confidently identified or tracked across sample sets as well as performing accurate quantitative comparison across sample sets.

Enhance your existing investment: nanoACQUITY UPLC and third-party mass spectrometers

Waters recognizes that a majority of labs have already made significant capital commitments to mass spectrometry equipment that may be manufactured by third-party providers. You can still take advantage of the significant benefits that the nanoACQUITY UPLC system offers as a front-end to a variety of MS instruments.

The nanoACQUITY UPLC system is now easily compatible with third-party MS solutions via expanded software control options, allowing you to get the most efficiency and performance from your existing technologies.

Maximise LC/MS performance and productivity

From Waters’ Quattro Premier XE tandem quadrupole mass spectrometer, for routine quantification to the Synapt™ High Definition MS (HDMS™) system for cutting edge applications, the nanoACQUIT Y UPLC system is the only inlet you’ll need for high-sensitivity nano-scale MS analyses, when sample-limited.nanoACQUIT Y UPLC system’s dramatic chromatographic resolution results in greatly enhanced detection sensitivity, allowing you to see more quality information in less time.

By matching our nano-scale UPLC/MS system solutions with MassLynx™ software for specialized data processing, you will complete your analysis accurately, quickly and with complete confidence in your answers.

Why purchase used refurbished
mass specs from KRSS

KRSS Ltd offer high quality pre-owned Mass Spec, LCMS, GCMS, HPLC and GC systems allowing affordable entry into a rapidly developing market.

All KRSS instruments are thoroughly inspected by ex-manufacturer or KRSS trained (including all components and parts), cleaned and decontaminated, completely refurbished (defective parts and components are replaced with genuine parts), serviced and bench tested to ensure the equipment meets our Used | Refurbished | KRSS Approved specifications - this guarantees quality, performance and reliability at a fraction of the OEM costs.

With over 50 instruments in stock, covering all major manufacturers KRSS has systems for a variety of application requirements. All instruments are supplied with a comprehensive warranty and optional service contracts to ensure trouble free operation.